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Jatin M. Vyas

Researcher at Harvard University

Publications -  113
Citations -  10622

Jatin M. Vyas is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Innate immune system. The author has an hindex of 31, co-authored 96 publications receiving 9378 citations. Previous affiliations of Jatin M. Vyas include Anschutz Medical Campus & Massachusetts Institute of Technology.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

Jan Hendrik Niess, +11 more
- 14 Jan 2005 - 
TL;DR: A myeloid-derived mucosal DC in mice is identified, which populates the entire lamina propria of the small intestine, and CX3CR1-dependent processes, which control host interactions of specialized DCs with commensal and pathogenic bacteria, may regulate immunological tolerance and inflammation.
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The known unknowns of antigen processing and presentation

Jatin M. Vyas, +2 more
- 01 Aug 2008 - 
TL;DR: The principal components of both MHC class I and class II antigen processing and presentation pathways are well known, but the exact mechanisms involved in the subcellular trafficking of antigens remain poorly understood.
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Antigen Presentation by Major Histocompatibility Complex Class I-B Molecules

Said M. Shawar, +3 more
- 01 Jan 1994 - 
TL;DR: It is argued that the dichotomous categorization of MHC genes as class I-a and I-b is conceptually misleading, despite its historical basis and practical usefulness, and is discussed with particular attention to their structure, polymorphism, requirements for peptide antigen binding and tissue expression.
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The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium

Alan Huett, +9 more
- 13 Dec 2012 - 
TL;DR: This work identifies LRSAM1 as the E3 ligase responsible for anti-Salmonella autophagy-associated ubiquitination and identifies it as a bacterial recognition protein and ubiquitin ligase that defends the cytoplasm from invasive pathogens.