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Mian Wu

Researcher at Henan University

Publications -  134
Citations -  14299

Mian Wu is an academic researcher from Henan University. The author has contributed to research in topics: Gene & Mutant. The author has an hindex of 49, co-authored 134 publications receiving 12487 citations. Previous affiliations of Mian Wu include National University of Singapore & University of Science and Technology of China.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

Peng Jiang, +7 more
- 01 Mar 2011 - 
TL;DR: It is shown that the tumour suppressor p53, the most frequently mutated gene in human tumours, inhibits the pentose phosphate pathway (PPP), which suppresses glucose consumption, NADPH production and biosynthesis.
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Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

Fan Yang, +3 more
- 09 Jan 2014 - 
TL;DR: It is shown that lincRNA-p21 is a hypoxia-responsive lncRNA and is essential for hypoxIA-enhanced glycolysis and the ability of lincRNAs to promote tumor growth is validated in mouse xenograft models and implicate linc RNA- p21 as a valuable therapeutic target for cancer.
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Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

Shanshan Feng, +7 more
- 01 Oct 2007 - 
TL;DR: It is shown that RIP3 is cleaved at Asp328 by caspase-8 under apoptotic stimuli, which is blocked by pan-caspase inhibitor Z-VAD-FMK, and the cleaved product of RIP3 (aa 329-518) displays better stability than wild type RIP3.
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Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis.

Zhiyin Song, +2 more
- 20 Jun 2003 - 
TL;DR: Evidence for the first time is provided that the interaction between Smac/DIABLO and Survivin is an essential step underling the inhibition of apoptosis induced by Taxol.