scispace - formally typeset
X

Xin Wang

Researcher at Brigham and Women's Hospital

Publications -  193
Citations -  11328

Xin Wang is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Medicine & Neuroprotection. The author has an hindex of 39, co-authored 146 publications receiving 9654 citations. Previous affiliations of Xin Wang include Harvard University & Life Sciences Institute.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease.

Xin Wang, +8 more
- 02 Sep 2003 - 
TL;DR: It is shown that minocycline is a drug that directly inhibits both caspase-independent and -dependent mitochondrial cell death pathways, and the mechanism by which minocyCline mediates its remarkably broad neuroprotective effects is delineated.
Journal ArticleDOI

Impaired Contextual Modulation of Memories in PTSD: An fMRI and Psychophysiological Study of Extinction Retention and Fear Renewal

Sarah N. Garfinkel, +6 more
- 01 Oct 2014 - 
TL;DR: PTSD patients showed a globally diminished capacity to use contextual information to modulate fear expression, and could not use safety context to sustain suppression of extinguished fear memory, but they also less effectively used danger context to enhance fear.
Journal ArticleDOI

Increase of Oxidatively Modified Protein Is Associated With a Decrease of Proteasome Activity and Content in Aging Epidermal Cells

Isabelle Petropoulos, +7 more
- 01 May 2000 - 
TL;DR: The results suggest that proteasome is downregulated during replicative senescence as well as in aged cells in vivo, possibly resulting in the accumulation of modified proteins.
Journal ArticleDOI

The antiapoptotic activity of melatonin in neurodegenerative diseases.

Xin Wang
- 01 Dec 2009 - 
TL;DR: This review summarizes the reports to date showing inhibition by melatonin of the intrinsic apoptotic pathways in neurodegenerative diseases including stroke, Alzheimer disease, Parkinson disease, Huntington disease, and amyotrophic lateral sclerosis.