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Baris Bingol

Researcher at Genentech

Publications -  27
Citations -  8783

Baris Bingol is an academic researcher from Genentech. The author has contributed to research in topics: Ubiquitin & Ubiquitin ligase. The author has an hindex of 15, co-authored 27 publications receiving 7688 citations. Previous affiliations of Baris Bingol include California Institute of Technology & Picower Institute for Learning and Memory.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

TL;DR: In this paper, Parkin ubiquitinates and tags damaged mitochondria for clearance, and USP30, a deubiquitinase localized to mitochondria, antagonizes mitophagy driven by the ubiquitin ligase parkin.
Journal ArticleDOI

Activity-dependent dynamics and sequestration of proteasomes in dendritic spines

TL;DR: In this paper, the authors used restricted photobleaching of individual spines and dendritic shafts to reveal the dynamics that underlie proteasome sequestration, and showed that activity modestly enhances the entry rate of proteasomes into spines while dramatically reducing their exit rate.
Journal ArticleDOI

Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease

Baris Bingol, +1 more
- 13 Jan 2011 - 
TL;DR: The mechanisms and functions of proteolysis in synaptic plasticity are highlighted and its alteration in disease states are discussed.