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Sofie Claerhout

Researcher at Katholieke Universiteit Leuven

Publications -  21
Citations -  6823

Sofie Claerhout is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Biology & Population. The author has an hindex of 12, co-authored 17 publications receiving 6054 citations. Previous affiliations of Sofie Claerhout include Flanders Institute for Biotechnology.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria

Ellen Wirawan, +14 more
- 01 Jan 2010 - 
TL;DR: Findings point to a mechanism by which casp-dependent generation of Beclin-1-C creates an amplifying loop enhancing apoptosis upon growth factor withdrawal.
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Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Annelien Verfaillie, +17 more
- 09 Apr 2015 - 
TL;DR: Using regulatory landscapes and in silico analysis, it is shown that transcriptional reprogramming underlies the distinct cellular states present in melanoma and reveals an essential role for the TEADs, linking it to clinically relevant mechanisms such as invasion and resistance.
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The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Inge Mannaerts, +9 more
- 01 Sep 2015 - 
TL;DR: YAP activation is a critical driver of hepatic stellate cell activation and inhibition of YAP presents a novel approach for the treatment of liver fibrosis.
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Arbuscular mycorrhizal fungi reduce root-knot nematode penetration through altered root exudation of their host

Christine Vos, +7 more
- 01 May 2012 - 
TL;DR: Nematode penetration was reduced in mycorrhizal tomato roots and mycorRhizal root exudates probably contributed at least partially by affecting nematode motility.