László Orosz

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is shown that TOR deficiency in the nematode Caenorhabditis elegans more than doubles its natural lifespan, suggesting a new function for TOR signalling in ageing control may represent a link between nutrition, metabolism and longevity.

TL;DR: It is demonstrated that mutational inactivation of autophagy genes, which are involved in the degradation of aberrant, damaged cytoplasmic constituents accumulating in all aging cells, accelerates the rate at which the tissues age in the nematode Caenorhabditis elegans and may act as a central regulatory mechanism of animal aging.

TL;DR: A number of temperature-sensitive and lysis-deficient mutants were isolated from a bacteriophage of Rhizobium meliloti and functions were classified in relation to the eclipse and latent period.