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Roland Malli

Researcher at Medical University of Graz

Publications -  158
Citations -  11730

Roland Malli is an academic researcher from Medical University of Graz. The author has contributed to research in topics: Mitochondrion & Endoplasmic reticulum. The author has an hindex of 41, co-authored 137 publications receiving 10196 citations. Previous affiliations of Roland Malli include University of Graz.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport.

TL;DR: It is demonstrated that UCP2 and UCP3 are elementary for mitochondrial Ca(2+) sequestration in response to cell stimulation under physiological conditions - observations supported by isolated liver mitochondria of Ucp2(-/-) mice lacking ruthenium red-sensitive Ca( 2+) uptake.
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Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

TL;DR: It is demonstrated that OxPAPC induces TF expression in HUVECs through activation of PKC/ERK/EGR-1 and Ca(++)/calcineurin/NFAT pathways rather than by NF-kappa B-mediated transcription, indicating that oxidized phospholipids may contribute to inflammation by activating pathways alternative to the classical NF- kappa B pathway.