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Samisubbu R. Naidu

Researcher at Indiana University

Publications -  19
Citations -  5745

Samisubbu R. Naidu is an academic researcher from Indiana University. The author has contributed to research in topics: Glycolysis & PKM2. The author has an hindex of 11, co-authored 18 publications receiving 5227 citations. Previous affiliations of Samisubbu R. Naidu include University of Massachusetts Medical School.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells

TL;DR: A novel function of the evolutionarily conserved chromatin remodeling subunit BRG1 is demonstrated, which cooperates with CBP to constrain p53 activity and permit cancer cell proliferation.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 - 
Journal ArticleDOI

Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 domain Mediated PUMA Degradation

TL;DR: It is shown that a lysosome-independent activity of chloroquine prevents degradation of PUMA protein, promotes apoptosis and reduces the growth of melanoma xenografts in mice.
Journal ArticleDOI

PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.

TL;DR: Together the collaborative role of the SUMO E3 ligase PIASy and the lysine acetyltransferase Tip60 act as a “binary death signal” to promote cytoplasmic accumulation of p53 and execution of PUMA-independent autophagy.