Lynda A. Morrison

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Treatment of the target cells with the lysosomotropic agent chloroquine abolished recognition of infected target cells by class II-restricted CTL without diminishing class I-restricted recognition ofinfected target cells, suggesting that important differences may exist in requirements for antigen presentation between H-2K/D and H- 2I region- restricted CTL.

TL;DR: The authors' observations on the cellular immune response to type-A influenza suggest the existence of two distinct pathways of protein antigen presentation to T lymphocytes, one of which is involved with presentation of antigens introduced into the presenting cell from without and the second which is tentatively designated as an endogenous presentation pathway.

TL;DR: The data suggest that inactivation of IL-18, and subsequent impairment of NK cell cytotoxicity, may be one mechanism by which ectromelia evades the host immune response.

TL;DR: Results demonstrate that an enteric virus entering a host from the intestinal lumen can spread to the central nervous system through nerve fiber innervating the intestine.