Shuo Wang

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: A regulatory subpopulation of ILCs exists in the gut and harbors a unique gene identity that is distinct from that of I LCs or regulatory T cells (Tregs), which play an inhibitory role in the innate immune response, favoring the resolution of intestinal inflammation.

TL;DR: A circular RNA is defined that was highly expressed in the nucleus of long‐term (LT)‐HSCs that protected dormant HSCs from type I interferon (IFN)‐mediated exhaustion and is a potent suppressor of cGAS‐mediated recognition and autoimmune response.

TL;DR: The data indicate that mammalian target of rapamycin (mTOR) is downregulated by Sox2 at an early stage of iPSC generation and that this transient downregulation of mTOR is required for reprogramming to take place.

TL;DR: It is shown that WASH deficiency causes early embryonic lethality and extensive autophagy of mouse embryos and WASH can suppress Beclin 1 ubiquitination to inactivate Vps34 activity leading to suppression of autophophagy.