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Takayuki Tsukuba

Researcher at Nagasaki University

Publications -  107
Citations -  8004

Takayuki Tsukuba is an academic researcher from Nagasaki University. The author has contributed to research in topics: Cathepsin E & Osteoclast. The author has an hindex of 31, co-authored 102 publications receiving 7291 citations. Previous affiliations of Takayuki Tsukuba include Kyushu University & Pennsylvania State University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways

Jin Ping Hu, +6 more
- 02 Feb 2008 - 
TL;DR: Findings indicate that berberine inhibits osteoclast formation and survival through suppression of NF-kappaB and Akt activation and that both pathways in the osteOClast lineage are highly sensitive to berberines treatment.
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Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalis.

Koji Nakayama, +5 more
- 01 Jan 1998 - 
TL;DR: Results strongly indicate a close relationship among HGP15 production, haemoglobin adsorption and haem accumulation of P. gingivalis.
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Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.

Tomoko Kadowaki, +9 more
- 01 Dec 2004 - 
TL;DR: Results indicate that the newly developed KYT-1 andKYT-36 both should provide a broader application in studies of this important class of enzymes and facilitate the development of new approaches to periodontal diseases.
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Increased Expression of Cathepsins E and D in Neurons of the Aged Rat Brain and Their Colocalization with Lipofuscin and Carboxy‐Terminal Fragments of Alzheimer Amyloid Precursor Protein

Hiroshi Nakanishi, +8 more
- 18 Nov 2002 - 
TL;DR: Results indicate that aging results in the increased expression and lysosomal localization of CE in cortical and brainstem neurons and changes in the endosomal/lysosomal proteolytic system, which may be related to lipofuscinogenesis and altered intracellular APP metabolism.