scispace - formally typeset
A

Andrea Viale

Researcher at University of Texas MD Anderson Cancer Center

Publications -  60
Citations -  11078

Andrea Viale is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Biology & Cancer. The author has an hindex of 24, co-authored 48 publications receiving 9597 citations. Previous affiliations of Andrea Viale include European Institute of Oncology & Harvard University.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

Haoqiang Ying, +30 more
- 27 Apr 2012 - 
TL;DR: In vivo mechanistic insights are provided into how oncogenic Kras promotes metabolic reprogramming in native tumors and illuminates potential metabolic targets that can be exploited for therapeutic benefit in PDAC.
Journal ArticleDOI

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

Andrea Viale, +29 more
- 30 Oct 2014 - 
TL;DR: It is demonstrated that a subpopulation of dormant tumour cells surviving oncogene ablation (surviving cells) and responsible for tumour relapse has features of cancer stem cells and relies on oxidative phosphorylation for survival.
Journal ArticleDOI

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

Avnish Kapoor, +30 more
- 03 Jul 2014 - 
TL;DR: It is shown that some tumors undergo spontaneous relapse and are devoid of Kras(G12D) expression and downstream canonical MAPK signaling and instead acquire amplification and overexpression of the transcriptional coactivator Yap1.
Journal ArticleDOI

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway.

Alessandra Insinga, +9 more
- 01 Jan 2005 - 
TL;DR: Results show that sensitivity to HDACIs in leukemias is a property of the fully transformed phenotype and depends on activation of a specific death pathway.