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Thomas S. Jacques

Researcher at Great Ormond Street Hospital for Children NHS Foundation Trust

Publications -  263
Citations -  19894

Thomas S. Jacques is an academic researcher from Great Ormond Street Hospital for Children NHS Foundation Trust. The author has contributed to research in topics: Cortical dysplasia & Gene. The author has an hindex of 49, co-authored 244 publications receiving 16159 citations. Previous affiliations of Thomas S. Jacques include Great Ormond Street Hospital & University of Cambridge.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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DNA methylation-based classification of central nervous system tumours

David Capper, +171 more
- 22 Mar 2018 - 
TL;DR: This work presents a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and shows that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods.
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The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

Ingmar Blümcke, +31 more
- 01 Jan 2011 - 
TL;DR: Focal cortical dysplasias (FCD) are localized regions of malformed cerebral cortex and are very frequently associated with epilepsy in both children and adults.
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International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods

Ingmar Blümcke, +22 more
- 01 Jul 2013 - 
TL;DR: The proposed international consensus classification of hippocampal neuronal cell loss will aid in the characterization of specific clinicopathologic syndromes, and explore variability in imaging and electrophysiology findings, and in postsurgical seizure control.
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Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

Ingmar Blümcke, +74 more
- 25 Oct 2017 - 
TL;DR: In patients with drug‐resistant focal epilepsy requiring surgery, hippocampal sclerosis was the most common histopathological diagnosis among adults, and focal cortical dysplasia was the second most common lesion in both groups.