Avital Eisenberg-Lerner

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The cross-talk between apoptosis and autophagy is a key factor in the outcome of death-related pathologies such as cancer, its development and treatment, and the molecular regulators of both pathways are inter-connected.

TL;DR: The intricate nature of autophagy and its regulators, particularly those that have been linked to cancer, are described and studies supporting a role for Autophagy in both tumor-suppression and tumor-progression are highlighted.

TL;DR: It is shown that, in the absence of netrin-1, recruitment of PP2A to UNC5H2/B allows the activation of DAPk via aPP2A-mediated dephosphorylation and that this mechanism is involved in angiogenesis regulation.

TL;DR: KDP is described as a novel Vps34 kinase that functions as an effecter of autophagy under oxidative stress, and it is shown that PKD is recruited to LC3-positive autophagosomes, where it localizes specifically to the Autophagosomal membranes.