scispace - formally typeset
R

Régis Delage-Mourroux

Researcher at University of Franche-Comté

Publications -  53
Citations -  8139

Régis Delage-Mourroux is an academic researcher from University of Franche-Comté. The author has contributed to research in topics: Autophagy & GABARAP. The author has an hindex of 24, co-authored 52 publications receiving 7333 citations. Previous affiliations of Régis Delage-Mourroux include University of Burgundy & French Institute of Health and Medical Research.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

TL;DR: This review will focus on the regulatory role of reactive oxygen species (ROS) and autophagy levels during the course of cancer development, from cellular transformation to the formation of metastasis.
Journal ArticleDOI

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

TL;DR: A clone from breast cancer cells is isolated from which it potentiates the inhibitory activities of dominant negative ERs and antiestrogen-liganded ER, and its direct interaction with liganded ER suggest that it may play an important role in determining the sensitivity of estrogen target cells, including breast cancer Cells, to antiestrogens and estrogens.
Journal ArticleDOI

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology.

TL;DR: Among several new ER-regulated genes, quinone reductase (QR), a detoxifying phase II antioxidant enzyme, is found that has its activity up-regulated by antiestrogens in an ER-dependent manner in breast cancer cells, thus showing 'reversed pharmacology'.
Journal Article

Estrogen receptors: selective ligands, partners, and distinctive pharmacology.

TL;DR: Findings indicate that different residues of the ER hormone-binding domain are involved in the recognition of structurally distinct estrogens and anti-estrogens and highlight the exquisite precision of the regulation of ER activities by ligands.