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Jane J. Yu

Researcher at University of Cincinnati Academic Health Center

Publications -  94
Citations -  9767

Jane J. Yu is an academic researcher from University of Cincinnati Academic Health Center. The author has contributed to research in topics: Lymphangioleiomyomatosis & mTORC1. The author has an hindex of 34, co-authored 76 publications receiving 8430 citations. Previous affiliations of Jane J. Yu include Harvard University & Dalian Institute of Chemical Physics.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4

Alfred Csibi, +15 more
- 09 May 2013 - 
TL;DR: It is shown that mTORC1 promotes glutamine anaplerosis by activating glutamate dehydrogenase (GDH) and this data indicate that targeting nutrient metabolism in energy-addicted cancers with high m TORC1 signaling may be an effective therapeutic approach.
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Isolation and characterization of the cDNA encoding human DNA methyltransferase

Ray Whay Chiu Yen, +9 more
- 11 May 1992 - 
TL;DR: The arrangement of multiple motifs conserved in the prokaryotic genes is preserved in the human DNA MTase, including the relative position of a proline-cysteine dipeptide thought to be an essential catalytic site in all (cytosine-5)-methyltransferases.
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The Maize Phytoene Synthase Gene Family: Overlapping Roles for Carotenogenesis in Endosperm, Photomorphogenesis, and Thermal Stress Tolerance

Faqiang Li, +4 more
- 01 Jul 2008 - 
TL;DR: Carotenoids are essential for photosynthesis and photoprotection; they also serve as precursors to signaling molecules that influence plant development and biotic/abiotic stress responses and are targets for metabolic breeding/engineering, particularly in the Poaceae family, which includes the major food crops.
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Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

Hongjing Gu, +17 more
- 27 Jan 2016 - 
TL;DR: It is demonstrated that angiotensin-converting enzyme-2 (ACE2) protected against severe lung injury induced by RSV infection in an experimental mouse model and in pediatric patients, and suggested that ACE2 is a promising potential therapeutic target in the management of RSV-induced lung disease.