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Yong J. Lee

Researcher at University of Pittsburgh

Publications -  201
Citations -  14626

Yong J. Lee is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Heat shock protein. The author has an hindex of 52, co-authored 193 publications receiving 13460 citations. Previous affiliations of Yong J. Lee include Beaumont Hospital & UPRRP College of Natural Sciences.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species

Shivendra V. Singh, +12 more
- 20 May 2005 - 
TL;DR: The results of the present study indicate that SFN-induced apoptosis in prostate cancer cells is initiated by ROS generation and that both intrinsic and extrinsic caspase cascades contribute to the cell death caused by this highly promising cancer chemopreventive agent.
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Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?

Douglas R. Spitz, +4 more
- 25 Jan 2006 - 
TL;DR: It is proposed that intracellular oxidation/reduction reactions involving hydroperoxides and thiols may provide a mechanistic link between metabolism, signal transduction, and gene expression in these human tumor cells.
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Effects of low dose quercetin: cancer cell-specific inhibition of cell cycle progression.

Jaehoon Jeong, +4 more
- 01 Jan 2009 - 
TL;DR: It is proved that the chemo‐preventive efficacy of a physiologically relevant dose of quercetin can be achievable through the inhibition of cell cycle progression.
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S-Glutathiolation of Ras Mediates Redox-sensitive Signaling by Angiotensin II in Vascular Smooth Muscle Cells

Takeshi Adachi, +7 more
- 09 Jul 2004 - 
TL;DR: The results show that H2O2 from NAD(P)H oxidase forms GSS-Ras on Cys118 and increases its activity leading to p38 and Akt phosphorylation, which contributes to the induction of protein synthesis.