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Ming Tan

Researcher at Georgetown University

Publications -  288
Citations -  21450

Ming Tan is an academic researcher from Georgetown University. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 57, co-authored 265 publications receiving 19070 citations. Previous affiliations of Ming Tan include University of Maryland, College Park & University of South Alabama.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Yoichi Nagata, +12 more
- 01 Aug 2004 - 
TL;DR: In this paper, PTEN activation contributes to trastuzumab's antitumor activity and PI3K inhibitors rescued PTEN loss-induced trastusumab resistance.
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Plasma phospholipids identify antecedent memory impairment in older adults

Mark Mapstone, +16 more
- 01 Apr 2014 - 
TL;DR: This work discovered and validated a set of ten lipids from peripheral blood that predicted phenoconversion to either amnestic mild cognitive impairment or Alzheimer's disease within a 2–3 year timeframe with over 90% accuracy and may be sensitive to early neurodegeneration of preclinical Alzheimer’s disease.
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Targeting cellular metabolism to improve cancer therapeutics

Yuhua Zhao, +2 more
- 07 Mar 2013 - 
TL;DR: The relationship between dysregulated cellular metabolism and cancer drug resistance is discussed and how targeting of metabolic enzymes can enhance the efficacy of common therapeutic agents or overcome resistance to chemotherapy or radiotherapy is discussed.
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Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis

Yan Michael Li, +13 more
- 01 Nov 2004 - 
TL;DR: It is shown that HER2 enhances the expression of CXCR4, which is required for HER2-mediated invasion in vitro and lung metastasis in vivo, and this work establishes a functional link between HER2 and CX CR4 signaling pathways.