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Martin E. Gleave

Researcher at University of British Columbia

Publications -  826
Citations -  51731

Martin E. Gleave is an academic researcher from University of British Columbia. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 110, co-authored 773 publications receiving 45346 citations. Previous affiliations of Martin E. Gleave include Chiba University & Vancouver General Hospital.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

Himisha Beltran, +25 more
- 01 Nov 2011 - 
TL;DR: There was dramatic and enhanced sensitivity of NEPC (and MYCN overexpressing PCA) to Aurora kinase inhibitor therapy both in vitro and in vivo, with complete suppression of neuroendocrine marker expression following treatment.
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Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

Jennifer A. Locke, +8 more
- 01 Aug 2008 - 
TL;DR: In this article, the authors show that all enzymes necessary for androgen synthesis are expressed in prostate cancer tumors and some seem to be up-regulated during prostate cancer progression, leading to AR activation.
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Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development.

Meritxell Gironella, +21 more
- 09 Oct 2007 - 
TL;DR: It is shown by immunohistochemical analysis that TP53INP1 expression is dramatically reduced in pancreatic ductal adenocarcinoma (PDAC) and this decrease occurs early during pancreatic cancer development and a previously unknown miR-155 target presenting anti-tumoral activity is presented.
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The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Charles E. Massie, +25 more
- 06 Jul 2011 - 
TL;DR: Cal calcium/calmodulin‐dependent protein kinase kinase 2 is highlighted, which it is shown is overexpressed in prostate cancer and regulates cancer cell growth via its unexpected role as a hormone‐dependent modulator of anabolic metabolism.