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Marc D. Meneghini

Researcher at University of Toronto

Publications -  32
Citations -  9123

Marc D. Meneghini is an academic researcher from University of Toronto. The author has contributed to research in topics: Saccharomyces cerevisiae & Histone. The author has an hindex of 15, co-authored 30 publications receiving 8520 citations. Previous affiliations of Marc D. Meneghini include University of Oregon & University of California, San Francisco.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Histone variant H2A.Z marks the 5' ends of both active and inactive genes in euchromatin.

TL;DR: In S. cerevisiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent heterochromatin to prevent its ectopic spread and enrichment at 5' ends is observed not only at actively transcribed genes but also at inactive loci.
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Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

TL;DR: Euchromatin and heterochromatin each contains components that antagonize switching to the opposite chromatin state and Htz1 is enriched in these euchromatic regions and acts synergistically with a boundary element to prevent the spread of heterochromeatin.
Journal ArticleDOI

The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF

TL;DR: It is shown that TAK1 activation stimulates NLK activity and downregulates transcriptional activation mediated by β-catenin and TCF, which negatively regulates the Wnt signalling pathway.
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A Protein Complex Containing the Conserved Swi2/Snf2-Related ATPase Swr1p Deposits Histone Variant H2A.Z into Euchromatin

TL;DR: A novel role for a member of the ATP-dependent chromatin remodeling enzyme family is revealed in determining the region-specific histone subunit composition of chromatin in vivo and controlling the epigenetic state of Chromatin.