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Rakesh Kumar

Researcher at George Washington University

Publications -  102
Citations -  9710

Rakesh Kumar is an academic researcher from George Washington University. The author has contributed to research in topics: Cancer & Chromatin remodeling. The author has an hindex of 38, co-authored 88 publications receiving 8669 citations. Previous affiliations of Rakesh Kumar include Washington University in St. Louis & University of Texas Southwestern Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow

Sarah A. Bliss, +12 more
- 01 Oct 2016 - 
TL;DR: It is reported that breast cancer cells prime MSC to release exosomes containing distinct miRNA contents, such as miR-222/223, which in turn promotes quiescence in a subset of cancer cells and confers drug resistance.
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MicroRNA-7, a Homeobox D10 Target, Inhibits p21-Activated Kinase 1 and Regulates Its Functions

Sirigiri Divijendra Natha Reddy, +3 more
- 15 Oct 2008 - 
TL;DR: It is established for the first time that Pak1 is a target of microRNA-7 and that HoxD10 plays a regulatory role in modifying the expression of miR- 7 and, consequently, the functions of themiR-7-Pak1 pathway in human cancer cells are established.
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Pak protein kinases and their role in cancer.

Bettina Dummler, +3 more
- 23 Jan 2009 - 
TL;DR: Paks are overexpressed and/or hyperactivated in several human tumors and their role in cell transformation makes them attractive therapeutic targets, and Pak-targeted therapeutics may efficiently inhibit certain types of tumors and efforts to identify selective Pak-inhibitors are underway.
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PAK Signaling in Oncogenesis

Poonam R. Molli, +4 more
- 16 Jul 2009 - 
TL;DR: The complex regulation of PAK and its downstream diverse myriads of effectors, which in turn are responsible for the biological effects ofPAK family of kinases in cancer cells are summarized.