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Lisa A. Brennan

Researcher at Florida Atlantic University

Publications -  42
Citations -  6989

Lisa A. Brennan is an academic researcher from Florida Atlantic University. The author has contributed to research in topics: Lens Fiber & Lens (anatomy). The author has an hindex of 21, co-authored 36 publications receiving 6290 citations. Previous affiliations of Lisa A. Brennan include Northwestern University & Ulster University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity

TL;DR: This study links the inhibitory action of NO with the destruction of zinc tetrathiolate cluster at the dimeric interface through S-nitrosylation of the cysteine residues.
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Increased Superoxide Generation Is Associated With Pulmonary Hypertension in Fetal Lambs. A Role for NADPH Oxidase

TL;DR: The results suggest that increased NADPH oxidase expression may increase levels of superoxide in persistent pulmonary hypertension of the newborn lung tissue, and that increased superoxide blunts vascular relaxations to exogenous NO while stimulating smooth muscle cell growth.
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Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations.

TL;DR: The potential role of mitochondrial function and redox balance in age-related eye diseases is outlined, and how the methionine sulfoxide reductase (Msr) protein repair system and other redox systems play key roles in the function and maintenance of the aging eye are detailed.
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The effect of vitamin C or vitamin E supplementation on basal and H2O2-induced DNA damage in human lymphocytes.

TL;DR: These supplementation regimens may be used to limit the possible adverse effects of reactive oxygen species (including those produced during the course of an immune response) on lymphocytes in vivo, and so help to maintain their functional capacity.